During this time I spent three summers working in an
organic chemistry laboratory. Among the drawers of
glassware and amber bottles of nasty-smelling chemicals, I
immersed myself in synthesizing two short amino acid
sequences. Articles relating to my research stuffed a
three-inch-thick navy blue binder. The cation-pi
interaction, bovine pancreatic trypsin inhibitor, unnatural
amino acids, native chemical ligation, high performance
liquid chromatography: I understood it all. But none of my
research, even if it had been successful, would have ever
appeared on one of those thousands of textbook pages. It
was too specialized.
Today's scientific research examines how the basic
principles apply to specific cases, searches for more
examples of a phenomenon, or fills in the details of a
process. These details are far from inconsequential. A
discovery about one tiny gene among the tens of thousands
that make up the human genome can save lives. Yet because
scientists now paint with tiny, delicate strokes instead of
broad splashes of color, they often find themselves backed
into corners.
Educational institutions encourage and even demand
specialization beginning at the undergraduate level. At
some universities biochemistry departments have broken away
from chemistry, astronomy from physics, molecular biology
from ecology and evolution. As an undergraduate the future
scientist selects a major, which may be bioinformatics,
chemical physics, or statistics as easily as biology,
chemistry, physics or math. Then he focuses even more
sharply while completing master's and/or Ph.D. degrees.
According to unwritten rules, a post-doctoral fellowship
should be in a different area. This means, however, that
someone who earned a Ph.D. in a DNA lab studies RNA in a
post-doc. He does not tag whales.
The system prepares scientists to be specialists, not
generalists, because being a generalist would drive a
scientist mad. B. L. Siegel said in 1984 that scientists
produce enough information every day to fill seven complete
sets of the Encyclopedia Britannica. I'd guess they're
finishing a dozen sets a day by now. The American Chemical
Society (ACS) introduced seven new journals in the past
five years alone. The ACS Style Guide lists abbreviations
for the 1000+ journals most frequently cited by its
members. They range from the widely known Science and
Nature to the extremely specific Cereal Chemistry and
Xenobiotica. And that's just chemistry. No one reads all
these journals. A typical scientist might flip through
Science or Nature each week, noting titles and reading two
or three articles closely. He might subscribe to a journal
or two specific to his field, and read it more closely. If
the media hypes a scientific discovery such as a new cancer
treatment or water on Mars, he will see it in his local
newspaper or on CNN. But most scientists remain wrapped up
in the specifics of their own fields and, specifically,
their own laboratories. To try to keep up with everything
is insanity.
The commercialization of science has also driven
specialization. Molecular biologists want to patent genes,
and organic chemists race to make potential drugs.
Scientists performing basic research scrounge for funding
as their applied counterparts form industry partnerships.
Commercialization depends on a scientific creation's
uniqueness. Thus, young scientists examine others' work
carefully, then carve out a unique niche with their
research projects. Everyone wants to break new ground, and
most want to sell it afterward. A scientist may break
ground in snail antennae or protactinium compounds, but he
owns the turf.
Acquiring funding is a huge hassle for scientists, and
specialization helps keep costs down. Newton merely needed
an apple, but today's experiments require Hubble Space
Telescopes and particle accelerators, which do not come
cheap. The amount of equipment needed for a project has
also skyrocketed. Gregor Mendel performed the experiments
that established the basic rules of heredity using pea
plants, pen, paper, a magnifying glass, tweezers, sunshine
and water. A friend of mine used in a plant genetics
experiment more than 50 chemicals, several computer
software programs, a cold room, incubators, a polymerase
chain reaction machine, a DNA sequencer, a centrifuge and
cooperative bacteria, not to mention the plants-all this to
investigate a mutation in one gene that causes abnormal
root development. After a scientist purchases a DNA
sequencer, economically he can't allow it to collect dust
while he works on something completely different. The
expensive equipment keeps scientists in the niches they
carve.
Sometimes a scientist attempts to venture out of his
specialization. But, fierce competition for grants means
that a biology proposal from a physics professor has little
chance of receiving funding. Scientists depend on grant
money to perform research which leads to publications which
leads to grant money and tenure. Some established researchers do slip into
a related field through collaborations with other scientists, but a
physicist will never become a biologist unless he halts his career to
obtain another degree.
Over the course of his career in the 1500s and 1600s,
Galileo researched magnetism, heat, microscopes, mechanics,
and astronomy. No one could do the same today. Too much
background material to read, too much equipment to buy, too
much time spent trying to convince people with money to
fund the projects. That's all right. A scientist can still
discover much of interest and even value in his little
corner of the universe.